Biochemical Studies on the Toxicity of Tetraethyl Lead and Other Organo-Lead Compounds

Lead and Lead Compounds

Further studies on the toxicity of some tetra and trialkyl lead compounds.

The toxicity of tetra and trimethyl and propyl lead compounds has been studied after their administration to rats and rabbits. The toxicity to rats of tetramethyl lead has been compared with tetraethyl lead when given by inhalation. Both tetramethyl and tetrapropyl lead were found to be considerably less toxic than trimethyl and tripropyl lead. There was evidence of a slow rate of conversion of...

Lead toxicity.

BACKGROUND Since the last In-Depth Review of lead toxicity in 2004 there have been further developments with regard to safe exposure levels for lead workers. AIMS To advise occupational health professionals of the latest research on the multi-system toxic effects of lead and the implications of this research for setting new safe and appropriate occupational suspension limits. METHODS An ext...

Diet and lead toxicity.

Introduction There is no known biological function for lead and any lead absorbed by man or by animal may be classified as potentially toxic. These toxic effects are many, ranging from morphological damage to tissues at higher concentrations, to lesser biochemical effects at lower concentrations. In biochemical systems lead will generally inhibit enzyme activity and result in clinical effects s...

The effect of methylmercury, tetraethyl lead, and sodium arsenite on the humoral immune response in mice.

The Effect of Methylmercury. Tetraethyl Lead. and Sodium Arsenite on the Humoral Immune Response in Mice. BLAKLEY. B. R .. SISODIA. C. S .. AND MUKKUR. T. K. ( 19801. Toxicol. Appl. Pharmacol. 52, 245-254. Male mice were exposed to methylmercury. tetraethyl lead. or sodium arsenite for 3 weeks in the drinking water at three or four con· centrations ranging from 0.5 to 10.0 ppm. The humoral comp...